||Number of Pages
||Asis Datta and V.P. Sharma
||Capital Publishing Company
||RECENT ADVANCE IN COMMUNICABLE AND NON-COMMUNICABLE DISEASES
Author: Asis Datta and V.P. Sharma
Description: It is almost impossible for us to picture the globe without pathogens and diseases. Though, new generation drugs for several diseases are easily accessible now, drug resistance and immuno-compromised situations pose a major threat to human health. Thus the need of the hour is to develop newer innovative targets followed by developing novel drugs against different diseases. It is imperative to develop integrated approaches in cell biology, molecular biology, gene expression and immunology to comprehend and unlock the fundamental issues in pathophysiology of various infectious diseases. Different chapters in this book highlight how different pathogens like Plasmodium, Mycobacterium, Salmonella, Leishmania etc. modulate the biology of the host cells for their survival by draining the essential nutrients from their respective hosts. Blocking these essential processes is compulsory to terminate the survival of the intracellular pathogens and thus could be a new way to develop potential therapeutic targets in the near future. The host-pathogen interactions highlighted in this book prove to a pertinent introspection of the pathobiology of different intracellular pathogens. This review, no doubt, will be very useful to impart a clear perception to the beginners as well as investigators working in the field.
Table of Content: * Modulation of intracellular trafficking pathways in host cells by intracellular pathogens * Bacterial pathogenesis and cancer: An adversarial relationship with opportunity for drug development * HABP1/p32/gC1qR gene as cytoadherent molecule that involves in bacterial invasion * Helicobater pylori: An overview of the infection, pathogenesis and molecular cell biology of DNAreplication and cell division * Tuberculosis: Current situation, challenges and intervention strategies * Tuberculosis: An emerging threat to humanity in India and elsewhere * Molecular diagnosis of tuberculosis, Ieishmaniasis and toxoplasmosis: The three intracellular pathogens * Malaria in India: Situation analysis and the way forward * Drugs and drug targets against malaria parasite * Recent advances in malaria drug discovery and development * Immune evasion by Leishmania parasite: Atale of subversion and exploitation * Different approaches in the quest to develop a successful vaccine against Ieishmaniasis * Leishmania, the causative agent of Kala Azar: DNAtransaction enzymes as possible drug targets * Cell death profile of a protozoan parasite: The Leishmania spp. * Leprosy: An overview * Preventing cholera * Recent advances in anthrax pathophysiology, prophylaxis and treatment * Genetic diversity and pathogenesis of human immunodeficiency virus with special emphasis on strains circulating in India * Radiation technology for preventing food-borne infections and intoxications of microbial origin * Genome organisation and gene regulation in Entamoeba histolytica * Amoebiasis and biology of Entamoeba histolytica * Candidiasis: Ayeast infection caused by Candida albicans * Animal transgenesis in the era of Omics * Diabetes in India-Existing trends, risk factors and emerging concerns * Lipid induced adipose tissue defects is associated with insulin resistance and type 2 diabetes * Genomic determinants of bilirubin level and hyperbilirubinemia pathologies